By Jennie R. Lill,Wendy Sandoval
The definitive advisor to the myriad analytical concepts on hand to scientists all for biotherapeutics research
Analytical Characterization of Biotherapeutics covers all present and rising analytical instruments and strategies used for the characterization of healing proteins and antigen reagents. From uncomplicated recombinant antigen and antibody characterization, to complicated analyses for more and more complicated molecular designs, the booklet explores the historical past of the research options and gives important insights into an important rising analytical options. additionally, it frames severe questions warranting awareness within the layout and supply of a healing protein, exposes analytical demanding situations which may take place while characterizing those molecules, and offers a couple of verified strategies.
The first single-volume consultant of its type, Analytical Characterization of Biotherapeutics brings jointly contributions from scientists on the innovative of biotherapeutics study and production. Key subject matters lined in-depth contain the structural characterization of recombinant proteins and antibodies, antibody de novo sequencing, characterization of antibody drug conjugates, characterization of bi-specific or different hybrid molecules, characterization of producing host-cell contaminant proteins, analytical instruments for biologics molecular review, and more.
- Each bankruptcy is written by means of a well-known specialist or specialists of their box who talk about present and leading edge techniques to totally characterizing biotherapeutic proteins and antigen reagents
- Covers the whole diversity of characterization techniques for giant molecule dependent therapeutics
- Provides an updated account of the newest ways used for giant molecule characterization
- Chapters hide the heritage had to comprehend the demanding situations handy, strategies to signify those huge molecules, and a precis of rising ideas for analytical characterization
Analytical Characterization of Biotherapeutics is an updated source for analytical scientists, biologists, and mass spectrometrists keen on the research of biomolecules, in addition to scientists hired within the prescribed drugs and biotechnology industries. Graduate scholars in biology and analytical technological know-how, and their teachers will locate it to be interesting and instructive supplementary reading.
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Additional info for Analytical Characterization of Biotherapeutics
Analytical Characterization of Biotherapeutics by Jennie R. Lill,Wendy Sandoval